Doctoral Researcher Microbial Communication (m/f)
- Master's degree (or equivalent) in chemistry or other natural and life sciences (e.g. chemical biology, biomedical sciences, biochemistry, etc.)
- Experience in lab work, either chemistry-, microbiology-, or molecular biology-oriented
- The candidate should embrace both working in an international research team and conducting research (team-oriented, as well as independent work) that covers multiple disciplines embedded in the infrastructure of the HKI
We are interested in understanding the role of bacterially produced natural products (i.e. small molecular weight compounds such as antibiotics) in biological systems. While new antibiotics are urgently needed to combat life-threatening infectious diseases, not much is known why these compounds are produced in an ecological setting. We investigate scenarios in which bacteria use natural products to defend themselves against microbial predators (e.g. amoebae). In particular, we are interested in understanding cooperative defence mechanisms by which several bacteria jointly combat their predator. The PhD project will involve the isolation of bioactive natural products as well as studies towards the understanding of when and why these molecules are produced. This project combines research in the fields of biological chemistry, natural product biosynthesis, and chemical ecology.