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SilcoTek GmbH

Dursan® - Bio-inert coating for Medical Equipment for the prevention of unwanted Protein sticking



Dursan® is a CVD-coating of intermolecularly-bonded silicon, carbon and oxygen atoms that creates a chemically inert, hydrophobic, anti-adhesive and corrosion resistant surface.

Prevention of biofouling and carryover effects

Dursan® coated parts prevent chemical interaction with the underlying substrate. Because of the coating's low surface energy proteins from biofluids such as blood won't stick to the surface. This increases the efficiency, accuracy and lifetime of equipment by reducing biofouling, bioaccumulation and carryover issues.

Our patented CVD-coating process creates a homogenous layer, less than 2000 nanometer that binds molecularly to the base substrates of stainless steel, glass and ceramic. Vapor deposition allows the coating to penetrate highly complex geometries and the smallest holes. Furthermore, Dursan's flexibility makes bending possible without damaging the coating (e.g. coated capillary tubes).

A recent study by Abbott Laboratories showed that a wash solution with non-ionic surfactant removed all residual BSA proteins from a Dursan® coated sensor surface while the same wash solution had no effect on Protein loading on bare stainless steel [1].

Medical Equipment
Dursan® coated fittings
Dursan® shows the following characteristics:

  • bio-inertness
  • homogenous, less than 2000 nm thin layer
  • hydrophobic
  • anti-adhesive
  • high acid and base-stability (pH 0-14)
  • temperature resistant up to 450°C
  • durable and corrosion resistant
  • flexible

bio-inertness
Average percent residue sticking rate/cleanability
of smaller bio-molecules (proteins) on Dursan®
and stainless steel tubes
The user will benefit from:

  • no protein sticking
  • prevention of carryover effects and false readings
  • improved lifetime of medical equipment
  • decreased cleaning effort and therefore cost effectiveness

Modify the surface of your equipment such as:

  • cost effectiveness
    Relative protein carryover: Dursan® significantly
    reduces carryover compared to conventional
    PEG coatings
    needles
  • liners
  • vials
  • bio sensors
  • capillary tubes
  • HPLC columns
  • auto sampling systems
  • and more....

For further information, please contact SilcoTek GmbH.

[1] A. Narvaez, S. Vaidya, D. Daghfal, M. Lawrence, M. Yuan, J. Mattzela, D. Smith - Reducing Adhesion of Proteins on Stainless Steel Components by the Application of a Carboxysilane Coating


SilcoTek GmbH
Schaberweg 23
D-61348 Bad Homburg

Fon: +49 (0)6172 / 279 718
Fax: +49 (0)6172 / 923 1347
Mail: Contact Kontakt
Web: www.silcotekgmbh.de


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