Dursan® - Bio-inert coating for Medical Equipment for the prevention of unwanted Protein sticking
Dursan® is a CVD-coating of intermolecularly-bonded silicon, carbon and oxygen atoms that creates a chemically inert, hydrophobic, anti-adhesive and corrosion resistant surface.
Prevention of biofouling and carryover effects
Dursan® coated parts prevent chemical interaction with the underlying substrate. Because of the coating's low surface energy proteins from biofluids such as blood won't stick to the surface. This increases the efficiency, accuracy and lifetime of equipment by reducing biofouling, bioaccumulation and carryover issues.
Our patented CVD-coating process creates a homogenous layer, less than 2000 nanometer that binds molecularly to the base substrates of stainless steel, glass and ceramic. Vapor deposition allows the coating to penetrate highly complex geometries and the smallest holes. Furthermore, Dursan's flexibility makes bending possible without damaging the coating (e.g. coated capillary tubes).
A recent study by Abbott Laboratories showed that a wash solution with non-ionic surfactant removed all residual BSA proteins from a Dursan® coated sensor surface while the same wash solution had no effect on Protein loading on bare stainless steel [1].
- Dursan® coated fittings
Dursan® shows the following characteristics:
- bio-inertness
- homogenous, less than 2000 nm thin layer
- hydrophobic
- anti-adhesive
- high acid and base-stability (pH 0-14)
- temperature resistant up to 450°C
- durable and corrosion resistant
- flexible
- Average percent residue sticking rate/cleanability
of smaller bio-molecules (proteins) on Dursan®
and stainless steel tubes
The user will benefit from:
of smaller bio-molecules (proteins) on Dursan®
and stainless steel tubes
- no protein sticking
- prevention of carryover effects and false readings
- improved lifetime of medical equipment
- decreased cleaning effort and therefore cost effectiveness
Modify the surface of your equipment such as:
- needles
- liners
- Relative protein carryover: Dursan® significantly
reduces carryover compared to conventional
PEG coatings
- Relative protein carryover: Dursan® significantly
- bio sensors
- capillary tubes
- HPLC columns
- auto sampling systems
- and more....
For further information, please contact SilcoTek GmbH.
[1] A. Narvaez, S. Vaidya, D. Daghfal, M. Lawrence, M. Yuan, J. Mattzela, D. Smith - Reducing Adhesion of Proteins on Stainless Steel Components by the Application of a Carboxysilane Coating
Visit us at the following trade fair:
- analytica in Munich from 04/09/2024 - 04/12/2024 (hall A2.223)
- ACHEMA in Frankfurt am Main from 06/10/2024 - 06/14/2024 (hall 11.1 booth F19)
SilcoTek GmbH
Hessenring 83
D-61348 Bad Homburg
Fon: +49 6172 3884 10
Mail: Contact
Web: silcotek.de